The Aerosol Society organized its 30th DDL congress in Edinburgh from December 11 to 13.
It is a must-attend annual forum for scientists, academics, clinicians, regulatory and industry experts involved in the development of inhalation medication. On the program, five thematic sessions each with a combination of conferences by experts in the field of inhalation and by students working to advance respiratory science.
During this congress, Thierry Porée, scientific director of the OptimHal-ProtecSom Laboratory, presented at a conference our latest work on the inhalation chamber for CombiHaler® mechanical ventilation circuits. An innovation !
CombiHaler® is an inhalation chamber for mechanical ventilation. It enables the simultaneous administration of medication by a metered dose inhaler and a vibrating mesh nebulizer.
It is intended to be used in hospitals, intensive care, or home hospitalization.
Research and results of interest have been presented by the OptimHal-ProtecSom laboratory.
Heating and humidifying a mechanical ventilation circuit is needed to protect the lungs of patients under invasive respiratory assistance. However, heat and humidity reduce the dose of aerosols delivered to the patient. We assessed the impact of heat and humidity on in vitro drugs delivery using pressurized metered dose inhaler and vibrating mesh nebulizer with CombiHaler®
This work has demonstrated the advantage of using an inhalation chamber both with a vibrating mesh nebulizer and with a metered dose inhaler, in comparison with the usually used T-pieces.
It also demonstrated that switching off the heated humidifier located in a mechanical ventilation circuit during drug administration did not increase the delivered dose and that the position of the inhalation chamber in the heated and humidified mechanical ventilation circuit had an important influence on this delivered dose.